The action comes just three months right after the airline recommenced flights from Belfast Metropolis right after an absence of 11 many years.
Ryanair operates routes to Malaga, Alicante, Krakow, Warsaw, Gdansk and Milan from Belfast International.
A spokesman for the airport explained: “It is disappointing that Ryanair has now determined to withdraw operations from the whole Northern Ireland market place at the conclusion of October, getting variously experienced a existence in all three community airports in current many years.
“It has been a tough interval for aviation and a time when customers will need some steadiness and religion in the Northern Ireland air transport community.”
Before on Tuesday, main government Michael O’Leary explained the airline was set to strike its goal of carrying involving 90m and 100m passengers for the yr to March 2021. It flew 149m passengers in the yr to March 2019.
Shares rose jumped 2.1pc to €16.forty one in London, valuing the airline at €18.6bn.